2000 Academic All-State
| PLAYER | SCHOOL |
| Jeff Hammerbacher | Ft Wayne Canterbury |
| Erik Anderson | Wheeler |
| Chris Stephens | Yorktown |
| Matt Zipse | Homestead |
| Jim Olds | Lafayette Jefferson |
| Kevin McCall | Greencastle |
| Tony Bradford | Chesterton |
| Greg Niemesh | Frankfort |
| Brad Woodcox | Eastside |
| Eric Suding | Muncie Central |
| Shaun Liberman | Hagerstown |
| Josh Harrison | Tri Central |
| Mitch Labhart | Perry Central |
| Bob Shaver | North Central |
| Pat Daily | Andrean |
| Justin Hole | Wapahani |
| Aaron Merkel | Northeast DuBois |
| Mike McLaughlin | Lawrence North |
| Andrew Beer | Ft Wayne Northrop |
| Neal Wallace | North Vermillion |
| Justin Johnson | Eastern (Howard) |
| Eric Wright | Terre Haute South |
| Jon Edwards | Kouts |
| Andrew Lechleiter | Brebeuf |
| Matt Gross | New Haven |
| Brian Bales | Lowell |
| Matt Moore | Evansville Harrison |
| Shawn Windler | Benton Central |
| Andrew Histard | Bethany Christian |
| Kevin Wichman | Perry Central |
| David Poisson | Northwestern |
| Kevin Eninger | Ft Wayne Luers |
| Mike Mack | Eastside |
| Randy Scherer | Evansville North |
| Zac Hagemeyer | Bloomington North |
| Andrew Gordon | Hagerstown |
| Phil Collins | Greensburg |
| David Hodges | Madison Shawe |
| Dan Small | Lafayette Harrison |
| Joe Hinton | Hammond Morton |
| Michael Lahr | Evansville Mater Dei |
| Tony Quandt | New Haven |
| Derek Vanemon | Paoli |
| Chad Paskiewicz | Wes Del |
| Joel Novak | Anderson |
| Brad Wochomurka | Columbus East |
| Todd Windler | Benton Central |
| Blake Erdel | Brebeuf |
| R.J. Watson | Wawasee |
| Justin Tammany | Rochester |